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DePierro was born in the Bronx to Vincent (Neil) and Elizabeth Smith Zottoli. Louise was a retired clerk in the civil service unit in Yonkers City Hall.
DePierro is survived by her husband, Albert DePierro; children, Albert (Johanna), Kenneth and Lisa DePierro; a grandson; sister, Amy D'Avella; and many nieces and nephews. She was predeceased by her sister, Betty Devorsky.
Calling hours are Friday, Dec. 27 from 2 to 4 and 7 to 9 p.m. at the Flower Funeral Home Inc., 714 Yonkers Ave. A Mass will be celebrated at 11 p.m. Saturday, Dec. 28 at St. Eugene's Church.
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